Imaging Lab

Imaging Metrics Laboratory

Clinical trials demand consistent, precise, and repeatable measurements of lesions over time. Most clinical radiology interpretations do not report results for the same lesions over time, and adherence to standardized analysis criteria (RECIST, WHO, SWOG) is not consistent. Volumetric measurements are time-consuming to obtain and thus rarely performed. And more advanced measurements, such as reliably quantifying dynamic contrast-enhanced (DCE) MRI data, are not feasible to perform in the clinical domain.

The problem: imaging metrics are not a component of routine clinical cancer care—but are essential to clinical trials.

Centralized and Simplified

Data can be sent via the Internet (via DICOM or secure ftp transfer) or mailed on CD/DVD to us, where it is aggregated and stored. Data is analyzed by our analysts and radiologists, and results are made available via a secure web site. The web site allows easy data access by investigators, research assistants, site monitors, and auditors. Automated reporting tools allow data to be viewed in tabular format or graphed over time.

CT, MR, and PET data are supported, as well as multi-modality (PET-CT, MR-PET) image data.

Quality Assurance

A strict quality assurance process is used to provide reliable, consistent, and accurate data. Readers are familiar with measurement criteria, have practiced on test data, and statistically compared against themselves and others to determine the reliability of their reads.

Services

Advanced Visualization Laboratory (AVL)

Our advanced image processing laboratory allows efficient processing of CT, MR, and PET data into 3D and time-resolved (“4D�) models. The high capital cost and skilled technical labor make creating and maintaining an advanced visualization lab difficult for even high-volume sites. Lower volume sites can derive significant cost savings in outsourcing 3D reconstruction, while increasing billing and improve interpretation quality.